Unfortnately, it's actually not that simple. There is a lot going on in here. Since you have limited knowledge of Crsystal, it will probably take a bit of time for you to get working.
First off, to get the basic summaries working, create a new group based on Location. This will get you the formatting you want. Secondly, you want to put the records the Details section and right-click on them and choose Insert > Summary to get the subtotals in the Group Footer section. Then hide the Details section.
The next tricky part is counting the Males and Females. You need a 'Male' formula that returns 1 if the field is Male and the same for Female. Put each formula in its own column. It would be like:
if {table.Location} == 'Male' then
1;
Work on that for a while and see how much progress you make, then report back to let us know how its going.