Are you asking how YOU can run the report, or how a co-worker could run the report. If you want to run the report, just click the preview button on the toolbar and it opens a new tab to show you how the report will look. If you want others to run the report, there is a free Crystal Reports viewer you can download from the Business Objects website (unfortunately, I don't have the link) or you can export it to PDF, HTML, Word, etc. and let the user open it using one of those programs.

For each person to run the report with live data, they need a copy of Crystal Reports on each computer. Alternatively, you can get that CR Viewer program that is a free download from Business Objects. They can load your report in the viewer and refresh the data.